| 2D Property Histogram |
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Strong Correlation Example
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Two-dimensional histogram of the chemicals with respect to the number of rotatable bonds and
rigid segments in each. The diagonal and "thin" arrangement of the combined distribution
indicates that these two properties exhibit a strong positive correlation.
Of course, this is to be expected since rigid segments are specifically defined here as
the number of segments delimited by rotatable bonds.
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Moderate Correlation Example
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Two-dimensional histogram of the chemicals with respect to molecular weight and
calculated XLogP value, an estimate of the chemical’s water / oil partition coefficient
often used to approximate a chemical’s solubility and thus permeability through phospholipid,
biological membranes. The diagonal shape indicates a positive correlation between these two
properties, but the broad shape indicates a weak relationship.
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